Computational methods for cancer and single-cell biology

BIOINFORMATICS · SYSTEMS BIOLOGY · AI FOR BIOMEDICINE

I am Adrian Salavaty, a bioinformatician and systems biologist developing computational methods and open-source tools for single-cell, spatial and multi-omics cancer research.

Single-cell & spatial omics Cancer multi-omics Open-source method development

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Senior Bioinformatician & Senior Cancer Scientist · Peter MacCallum Cancer Centre · Melbourne

Portrait of Adrian Salavaty

About

PROFILE

Turning high-dimensional biological data into interpretable methods and tools.

I work at the intersection of bioinformatics, systems biology, cancer genomics and computational method development. My research focuses on extracting robust biological structure from complex omics data, particularly single-cell, spatial and multi-omics datasets.

At Peter MacCallum Cancer Centre, I work across translational cancer research and bioinformatics. I also develop open-source computational frameworks, including CelliVerse, ClustoCell, ExIR and influential, with an emphasis on methods that are interpretable, reusable and practical for researchers.

Research Focus

Computational approaches designed around biological questions, not software conventions.

Single-cell & Spatial Omics

Cell-state discovery, clustering, marker identification, annotation, spatial organisation and translational analysis.

Cancer Multi-omics

Integrated analysis of transcriptomic, proteomic and genomic data to resolve tumour biology and clinically relevant signals.

Systems & Network Biology

Graph-based modelling, network reconstruction, feature prioritisation and interpretable biological systems analysis.

AI-assisted Bioinformatics

Practical AI and agent workflows that make advanced analysis tools easier to use without obscuring the underlying evidence.

Research Software & Methods

Open-source computational tools, algorithms and interactive resources.

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Selected Publications & Preprints

Recent work across computational biology, single-cell analysis and systems biology.

Experience

Selected research and computational biology roles.

 
 
 
 
 
Bioinformatics Core Facility, Peter MacCallum Cancer Centre
Senior Bioinformatician
Nov 2024 – Present Melbourne, VIC, Australia
  • Single-cell, spatial and bulk omics analysis
  • Multi-omics integration and computational method development
  • Systems biology and translational cancer research
 
 
 
 
 
Audax (formerly oNKo-innate)
Senior Bioinformatics Scientist
Nov 2023 – Nov 2024 Melbourne, VIC, Australia
  • Omics and drug-screening analysis
  • Systems biology and machine learning
  • Computational pipeline development
 
 
 
 
 
Arta Bioanalytics
Scientific Advisor
Oct 2023 – Oct 2024 Sydney, Australia
Scientific advisory work in bioinformatics and data analysis.
 
 
 
 
 
Children’s Cancer Institute Australia
Research Officer (Bioinformatician and Systems Biologist)
Mar 2022 – Nov 2023 Sydney, Australia
  • Omics data analysis
  • Graph-based method development
  • Cancer risk, driver and biomarker discovery
 
 
 
 
 
ANUNA AI (formerly MEDDA)
Scientific Advisor
Oct 2021 – Sep 2023 USA
Scientific advisory work at the interface of biomedical data and AI.
 
 
 
 
 
Monash University
Tutor (TA)
Mar 2020 – Nov 2021 Melbourne, VIC, Australia
Teaching across bioinformatics, genomics and medical biotechnology units.

Recognition & Funding

2022
AWARD

Postgraduate Publication Award

Monash University recognition based on publication record and prospects.

2021
AWARD

Best Oral Talk, People’s Choice

COMBINE symposium.

2021
RESEARCH FUNDING

Monash Data Futures Institute Seed Grant

Named investigator on Finding the right targets: most influential nodes in complex networks.

What Collaborators Say

Selected excerpts from research supervisors and collaborators.

“Adrian has a particularly strong skill set in the development of interactive applications using RShiny and similar tools, often exceeding my expectations around what is possible.”
Joe CursonsComputational Biology Leader, Audax
“He has single-handedly transformed my group’s approach to computational systems biology, written new algorithms and invented completely new systems approaches.”
Peter CurrieProfessor and Group Leader, Monash University
“His outstanding analytical capabilities combined with innovative thinking places him in the top 1% of students.”
Mirana RamialisonAssociate Professor and Group Leader, MCRI

Excerpts shortened for the homepage. Full references can be provided when relevant.

Contact

For scientific collaboration, methods, software or speaking enquiries.